MLVA BASED CLASSIFICATION OF MYCOBACTERIUM TUBERCULOSIS COMPLEX LINEAGES FOR A ROBUST PHYLOGEOGRAPHIC SNAPSHOT OF ITS WORLDWIDE MOLECULAR DIVERSITY.

MLVA based classification of Mycobacterium tuberculosis complex lineages for a robust phylogeographic snapshot of its worldwide molecular diversity.

Multiple-locus variable-number tandem repeat analysis (MLVA) is useful to establish transmission routes and sources of infections for various microorganisms including Mycobacterium tuberculosis complex (MTC).The recently released SITVITWEB database contains 12-loci Mycobacterial Interspersed Repetitive Units--Variable Number of Tandem DNA Repeats (

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Proteomic changes to immune and inflammatory processes underlie lung preservation using ex vivo cytokine adsorption

IntroductionIn recent years, the field of graft preservation has made considerable strides in improving outcomes related to solid organ restoration and regeneration.Ex vivo lung perfusion (EVLP) in line with the related devices and treatments has yielded promising results within preclinical and clinical studies, with the potential to improve graft

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Exploring the Conformational Space of Bcl-2 Protein Variants: Dynamic Contributions of the Flexible Loop Domain and Transmembrane Region

Members of the Bcl-2 protein family regulate apoptosis through interactions with several proteins.A critical intrinsically disordered region (IDR) present in some members of the Bcl-2 family is essential for their function.Also, the structural and conformational plasticity of disordered regions is essential for the regulation of the Bcl-2 protein&#

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